Use DBCC FREEPROCCACHE to clear the procedure cache. Freeing the procedure cache would cause, for example, an ad-hoc SQL statement to be recompiled rather than reused from the cache. If observing through SQL Profiler, one can watch the Cache Remove events occur as DBCC FREEPROCCACHE goes to work. DBCC FREEPROCCACHE will invalidate all stored procedure plans that the optimizer has cached in memory and force SQL Server to compile new plans the next time those procedures are run.
Use DBCC DROPCLEANBUFFERS to test queries with a cold buffer cache without shutting down and restarting the server. DBCC DROPCLEANBUFFERS serves to empty the data cache. Any data loaded into the buffer cache due to the prior execution of a query is removed.