EXEC sp_CONFIGURE ‘clr enabled’ , ’1′
GO
RECONFIGURE;
GO

and everthing is fine…

In Older versions of SQL Server, yes this command needed a sql server instance restart. But From SQL Server 2005, if you use, RECONFIGURE WITH OVERRIDE, Restart is not needed.

For Ex:

EXEC sp_CONFIGURE ‘show advanced options’ , ’1′;
GO
RECONFIGURE WITH OVERRIDE
GO

EXEC sp_CONFIGURE ‘clr enabled’ , ’1′
GO
RECONFIGURE WITH OVERRIDE
GO

EXEC sp_CONFIGURE ‘show advanced options’ , ’0′;
GO
RECONFIGURE WITH OVERRIDE
GO

Also, You can do the same thing through, Surface Area Configuration.

Start – All Programs – Microsoft SQL Server 2005 – Configuration Tools – Surface Area Configuration – Surface area Configuration for features

Click on the SQL Server instance, Expand Database Engine for that SQL Server instance and then point to CLR Integration on right side of panel, Check the radio button, Click Ok.

You are done. This will also not require a restart of SQL Server Instance.

Good if you test this out of your DEV/ TEST Env, before making change in production.

~ IM.